Best nightlife in Soho: The hottest clubs and music venues

The best nightlife in Soho isn’t confined to clubs—much of the after-dark action takes place in live-music and other venues.

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Though the neighborhood isn’t generally known for hip clubs, Susanne Bartsch's long-running soiree, Vandam Sundays, at eco-themed Greenhouse is among the area’s best nightlife options. You can catch a gig at winery-cum-venue City Winery or global-music hot spot S.O.B.’s. Start (or end) your night at one of the area’s best bars.

RECOMMENDED: Full guide to Soho, New York

City Winery

  • Price band: 2/4

Unabashedly grown-up and yuppie-friendly, this slick new club launched by oenophile Michael Dorf, founder of the Knitting Factory, is New York’s only fully functioning winery, as well as a 350-seat concert space. Acts tend to be on the quiet side, but that doesn’t mean the shows lack bite. Younger singer-songwriters like Keren Ann and Diane Birch have appeared, but the place is dominated by older artists (David Johansen, Los Lobos).

  1. 155 Varick St, (at Vandam St)
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S.O.B.’s

The titular sounds of Brazil (S.O.B.—get it?) are just some of the many global genres that keep this spot hopping. Hip-hop, soul, reggae and Latin beats all figure in the mix, with Seu Jorge, Zap Mama and Wyclef Jean each appearing of late. The drinks are expensive, but the sharp-looking clientele doesn't seem to mind.

  1. 204 Varick St, (at W Houston St)
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Don Hill’s

Smack in the middle of the exclusive-club district, on the western end of Spring Street, is a rock & roll throwback to the days when girls wore their hair big and boys wore tapered pants and snapped their fingers. Velvet-rope discos be damned—this metal-head (or would that be mullet-head?) mecca allows you to dance to the best of the ’80s bands. Saturday is Britpop night.

  1. 511 Greenwich St, (at Spring St)
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