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Midtown East
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Chef Edwin Bellanco (Morrell Wine Bar & Cafe, Bouley) executes a European-American menu at this 110-seat restaurant. Perch on a cushy white-leather seat at the alder-wood bar and choose from more than 120 wines. In the main dining room and overlooking mezzanine, find pastas (wild-mushroom pappardelle), mains (rib eye, cocoa-crusted venison loin) and globe-trotting appetizers (terrines, tacos, crudo).

Venue name: Vitae
Address: 4 E 46th St
New York
Cross street: between Fifth and Madison Aves
Opening hours: Mon–Sat 11:30am–11pm, Sun 11:30am–3pm
Transport: Subway: 42nd St S, 4, 5, 6, 7 to 42nd St–Grand Central
Price: Average main course: $25. AmEx, Disc, MC, V
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