Hang off a cablecar, escape to Alcatraz, then sup an organic cocktail
Never mind the cocktails, the four-page menu alone is headspinning enough: sup a Ukrainian Quaalude or a Hairy Cherry.
Milk is one of San Francisco's best hip hop clubs. Big-name guests such as DJ Shadow have been known to drop in.
An outdoor piazza offers panoramic views of the San Francisco skyline, while its innovative interior includes floor-to-ceiling aquariums.
The Museum of Modern Art's vast collection includes works by René Magritte, Jeff Koons, and Marcel Duchamp. However, the special exhibitions are the real draw.
Once the world's most infamous prison, the ominous buildings today lure over a million visitors each year. The chilling audio tour features interviews with former prisoners.
This 210ft (64m) concrete turret, built in 1933, provides spectacular views from the top and is decorated with some wonderful murals, created under the supervision of Diego Rivera.
With more than a dozen film festivals, a parade to celebrate St Stupid, a 40,000-strong desert party within striking distance, and California's largest annual multi-cultural festival, San Fran loves – loves – to party.