The Hotel Drisco is a sophisticated and welcoming boutique hotel situated in the posh Pacific Heights neighborhood with luxury amenities like complimentary nightly wine receptions and a chauffeur service that runs to popular spots on weekdays. There's free wifi and 24-hour room service too, so you really needn't leave the hotel at all. If you do though, you'll find you're super close to Predisio National Park, which is oozing with natural beauty. A prime walking spot.
Time Out tip: The evening reception is not to be missed. There are local California wines, artisanal cheeses and charcuterie, fresh fruit and hot hors d’oeuvres.