One of only a handful of five-star hotels in the city, the Hyatt Regency stands out for its stunning architecture and location—inside one of two complementary glassy cube-like towers set on the tip of a peninsula overlooking the Rhine. The 303 contemporary rooms maximize the spectacular views through floor-to-ceiling windows, but the open concept might not be to everyone’s taste, with entry doors opening directly into the bathroom. All categories feature separate showers and bathtubs, separated by glass from the sleeping area (which can create privacy issues). A 24-hour gym boasts excellent Rhine views, and the Rive spa, with its large treatment rooms, uses all-natural Organic Pharmacy and SkinCeuticals products. There’s no pool, but a large whirlpool and wet and dry saunas offer plenty of space for relaxing. Other amenities include a top-notch restaurant, DOX, and two bars
Neighborhood: The formerly grungy industrial harbor Medienhafen has gotten a futuristic makeover, with shiny glass and stainless-steel buildings designed by starchitects like Frank Gehry and David Chipperfield. Swanky restaurants and bars line the river and nearby is the Rhine Promenade, a pedestrian thoroughfare that stretches for nearly a mile to the Old Town.
Rheinturm: For the best city views, an observation deck and rotating restaurant occupies the top level of Dusseldorf’s tallest building
The View Skylounge: For drinks with a view, plus a fashionable local crowd and evening DJs
Curry: For a taste of Germany’s national dish, currywurst
Time Out tip: The Sunday brunch buffet at the river-fronting DOX restaurant is pricey but worth every penny, with a massive selection of hot and cold dishes, soups, cheeses and pastries, plus an excellent sushi station.