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This New Mexico City has one of the most unique cocktail trails in the U.S.—and it’s rooted in 400 years of history

Santa Fe is home to the Margarita Trail, where history, art, and handcrafted cocktails all come together in one unforgettable experience.

Written by Abby PriceContributor, Time Out USA
Santa Fe, NM
Shutterstock | Santa Fe, NM
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Driving into Santa Fe feels completely different from what you might expect, especially the first time. Even before you reach the city, the drive begins to reflect Santa Fe’s blend of landscape, culture, and culinary traditions embodied by the Margarita Trail. As the miles pass by, the landscape slowly shifts into something that feels entirely its own.

While many travelers imagine the region as an endless desert, Santa Fe’s high elevation, sitting more than 7,000 feet above sea level, creates a surprisingly lush environment filled with rolling grasslands, piñon trees, and four distinct seasons.

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The farther you drive, the more dramatic the backdrop becomes, with the towering Sangre de Cristo Mountains rising in the distance. At the same time, adobe homes and earthy-toned buildings begin appearing along the roadside. By the time you reach the heart of the city, it feels as though you’ve stepped into another world entirely, one shaped by centuries of art, heritage, and tradition, unlike anywhere else in the United States. It’s also what makes the Santa Fe Margarita Trail feel less like a tourist attraction and more like an extension of daily life in the city.

Santa Fe, New Mexico
Photograph: New Mexico TrueSanta Fe, New Mexico

In a city where creativity and culture spill into nearly every corner, even something as simple as ordering a margarita becomes an experience rooted in storytelling, local ingredients, and Southwestern tradition.

To really understand the Margarita Trail, you have to look at the legacy that shaped it. Nicole Barker, Media Relations Manager at the New Mexico Tourism Department, said, “The connection between New Mexico and agave dates back centuries through the shared cultural and trade history of the Southwest and Mexico, particularly along the historic El Camino Real de Tierra Adentro.”

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She continued, “Long before tequila became globally recognized, agave-based spirits and traditions traveled north through these corridors, influencing Santa Fe's culinary identity. Today, the Santa Fe Margarita Trail celebrates that heritage by pairing the history of tequila and agave with the city’s distinctly New Mexican flavors, storytelling, and hospitality.”

Santa Fe, New Mexico
Photograph: ShutterstockSanta Fe, New Mexico

This background has helped shape Santa Fe into a destination known for its distinctive Southwestern cuisine and craft beverages. While Santa Fe holds a special place in my heart for its art, architecture, and flavors, one of my favorite ways to experience it today is through the Margarita Trail, where visitors can explore the city one signature cocktail at a time.

The Santa Fe Margarita Trail feels less like a tourist attraction and more like an extension of daily life in the city.

Nicole Barker captured it best, saying, “The Santa Fe Margarita Trail blends Santa Fe’s deep culinary heritage with the creativity of nearly 50 local restaurants and bars, each offering its own signature take on the margarita. With approximately 50 specialty margaritas featured across the trail—from elevated cocktails to longtime local favorites—it encourages visitors to explore Santa Fe’s culture, flavors, and neighborhoods at their own pace while celebrating a drink that has become synonymous with the destination.”

The Margarita Trail: Tequila and sangria at La Choza
Photograph: Abby Price for Time OutThe Margarita Trail: Tequila and sangria at La Choza

While you can easily explore the Margarita Trail without a passport, one of the most enjoyable ways to experience it is by picking one up at a downtown Santa Fe Visitor Center. Visitors can purchase a paper passport for $3 or download the app for $2.99, both of which offer a fun way to track stops along the trail and unlock a few added perks along the way.

When you present your passport at participating restaurants, you’ll receive $1 off their signature margarita. After enjoying your drink, be sure to ask your bartender or server for a stamp; each one brings you closer to rewards that make the experience even more memorable.

To encourage a relaxed pace, participants are limited to earning two stamps every 12 hours. But for those looking to explore over several days, the rewards can add up quickly. Five stamps earn a Margarita Trail T-shirt, while 30 stamps unlock a margarita bartender kit, along with additional prizes at various milestones in between. It’s a playful and fun way to experience New Mexico’s flavors while supporting local businesses along the way.

Coyote Cafe & Rooftop Cantina in Santa Fe, New Mexico
Photograph: Courtesy Tourism Santa FECoyote Cafe & Rooftop Cantina in Santa Fe, New Mexico

While you really can’t go wrong with any of the stops along the trail, some of my favorites that combine tasty margaritas and delicious food include La Choza and The Shed.

After you explore the Margarita Trail

If you’re looking to explore more of what makes Santa Fe so unique, or you simply need a break from all of the tangy tequila and flavorful food, one of the best places to visit is the New Mexico Museum of Art, a state-run museum dedicated to capturing the creativity of the Southwest and one that feels especially relevant this year.

Barker mentioned, “2026 is an opportune time to experience New Mexico as we celebrate the Route 66 Centennial alongside a renewed love for the great American road trip. The New Mexico Museum of Art’s new exhibition, Roadside Attractions, captures the spirit of the open road, with photographs of Route 66 over the decades, including neon signs, quirky roadside stops, and the landscapes that continue to make Route 66 an iconic component of American culture.”

Santa Fe, New Mexico
Photograph: Courtesy New Mexico TrueSanta Fe, New Mexico

As someone who completed the full Route 66 drive from Chicago to Santa Monica, I can say the museum is well worth a visit. It captures the spirit of the classic American road trip and thoughtfully celebrates the iconic route’s centennial, while also highlighting Santa Fe as a memorable stop along the journey. At just $12 to enter, it’s also a great way to spend an afternoon walking off some of the margaritas and Southwestern cuisine you’ll indulge in throughout the city.

Where to stay in Santa Fe

The La Posada de Santa Fe is thoughtfully located in the heart of the city, within walking distance of countless restaurants along the Margarita Trail and the New Mexico Museum of Art, making it the perfect home base for your city adventure. With its incredible adobe architecture, expansive six-acre grounds, and numerous inviting rooms and spaces, it offers plenty of space to wander, unwind, and take in the surroundings. It typically costs between $200 and $400 a night and is well worth it for its central location and walkability to most of what the city has to offer.

Santa Fe, New Mexico
Photograph: Courtesy New Mexico TrueSanta Fe, New Mexico
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