George and Amal Clooney spent their wedding night at this ultra-luxurious 1500s palace hotel on the Grand Canal, so it’s probably safe to assume that it’s fancy enough for the rest of us. Even the most basic of rooms are anything but, with sleek midcentury modern furnishings set against vintage floors, wall coverings, ceiling paintings and in some cases, priceless works of art. Several rooms and suites have canal views. Food and drink options include a gourmet restaurant, a clubby bar, or a garden lounge for cicchetti and a spritz.
Time Out tip: Room prices are sky-high, but consistent year-round. If you’re looking for a luxury Venice hotel in high season, you might find the best rates here.
Comune di Venezia: For the waterfront city hall where George and Amal tied the know
Estro: For modern cicchetti in a wine bar with a young, stylish vibe
Osteria da Fiore: For Michelin-starred dining in a low-key setting