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The history-steeped city of Cincinnati is beloved for its good manners, European-style neighborhoods and rich architecture, with buildings from the likes of Frank Gehry and Cesar Pelli. Artsy and prosperous, Cinci (as locals call it) has a wealth of theaters, art museums and music halls, and a booming culinary scene. A recent renaissance outside downtown has seen bars, coffee shops and boutique hotels pop up in formerly downtrodden areas such as Over-the-Rhine and Northside. While anonymous conference hotels still tend to dominate (albeit often in beautiful Art Deco buildings), a cluster of alternatives takes in a hip hotel in a former department store, a boutique spot that doubles as an art gallery, and a music-themed mansion. Be warned though – accommodation doesn’t come cheap. In fact, the city’s hotels have been ranked the most expensive in the Midwest.