This eye-popping art and science museum mesmerizes kids and adults alike. Reopened after massive renovations at Pier 15 in 2013, the museum touts over 500 exhibits, including hands-on activities, science experiments, and interactive galleries incorporating sight, touch, memory, and perception. The clever, mind-bending exhibits blend light, tricks of physics, and sound. Whether you’re ogling rare plants or awe-inspiring art (a sculpture made from 100,000 toothpicks?!), it’s easy to spend a full day here.