There's no shortage of brown-spirits peddlers in Williamsburg (Post Office, the Whiskey Brooklyn). But at this serious watering hole, whiskey joins forces with another resurgent epicurean darling—locavore grilled cheeses. Studious boozers can choose from more than 225 selections, including George Dickel Old No. 8 Tennessee Whisky, Johnnie Walker Blue Label and Old Potrero 19th Century Straight Rye Whiskey. Pair yours with one of seven melted-cheese sammies, like the Jane (New York sharp cheddar and My Friend’s Mustard on sourdough) or the Maefred (Brie, local mushrooms and rosemary on ciabatta), made with Orwasher's bread. The old-timey joint, which is named after a onetime Brooklyn creek, features a coffered ceiling, pine banquettes and lamps fashioned from amber medicine jars.