The French Room at Mihoko's 21 Grams

Veteran barman Raphael Reyes oversees the cocktail menu at this Flatiron bar. Look for French-Japanese tipples like the Lautrec Royal, a mixture of the Japanese plum liquor umeshu, champagne, lemon and pear juices, vodka and black lime (a Middle Eastern spice). Winos can choose from a selection of 450 bottles, plus 16 sakes. The monochromatic room—featuring white leather chairs and a marble bar—lends the space an haute cool.