The Ted Alexandro Show; Q.E.D., Astoria, 8pm. $5.
One of the New York comedy scene’s smartest, funniest mainstays interviews Zephyr Teachout at his brilliant monthly show.
Waka Flocka Flame; Webster Hall, Downtown, 8pm. $25.
Waka Flocka Flame turns up for what's sure to be the most boisterous 4/20 party in the five boroughs. If you can stop headbanging for a few seconds and pay attention, keep your ears perked for a preview of Flockaveli 2, due in June.
Neil Goldberg; Participant Inc, Lower East Side, 12pm. Free.
The Gay Couples of Whole Foods is one of the titles in this show of photos and drawings that contemplate our various relationship with food.
Application Pending; Westside Theatre, Hell's Kitchen, 8pm. $79.
Application Pending isn’t a musical, but Christina Bianco is something akin to a one-woman orchestra. In Greg Edwards and Andy Sandberg’s deliciously twisted solo vehicle, the multivoiced wonder and Forbidden Broadway vet morphs into 43 personalities, creating a symphony of hilariously harmonious voices.
Rob Cantrell & Murderfist Save the Earth: A 420 Spectacular; Knitting Factory, Williamsburg, 10am. $10.
You know we can't go a whole post without bringing to light the "light up" occasion. Celebrate 4/20 at Knitting Factory where highly talented comedians share their dope jokes with fellow Mary Jane fans.
Small Mouth Sounds; Ars Nova, Hells Kitchen, 7pm. $35–$45.
Though it employs very little dialogue, there’s nothing quiet about Small Mouth Sounds. Bess Wohl’s luminous new play uses silence to dig into the core of human pain, which, like everything unendurable, can also be very funny.
Force Majeure; The Cobra Club, Bushwick, 8:30pm. $10.
This talent extravaganza goes beyond the typical variety show, with burlesque show, drag, comedy plus performances by magician Tanya Solomon and "vocal cartoonist" (or mime) Zero Boy.
"Sultans of Deccan India, 1500–1700: Opulence and Fantasy": The Metropolitan Museum of Art, Central Park, 10am. $25.
See treasures made of the powerful rulers of central India.
Heems + Weekend Money + Topaz Jones + Kahli Abdu + VHS Safari; Baby's All Right, Williamsburg, 8pm. $15, advance $12.
Queen's own Himanshu Suri, of former Das Racist, headlines, with songs from his new LP, Eat, Pray, Thug. If any of his new tunes are as catchy as "Combination Pizza Hut and Taco Bell," you're in for a treat.
The Great Street Meet; Judson Memorial Church, Greenwich Village, 6:30pm. $35-$500.
Hit the pavement and grub on eats from dozens of vendors from across all five boroughs. Make sure to stop by Knish Bakery celebrating 105 years in the baking business since it pushcart beginnings.
In Stereo: Two Comics One Stage; HiFi, East Village, 8pm. Free.
Comedian couple Naomi Elkerigin (Broad City) and Andy Beckerman (The Pete Holmes Show) presents stand up performed by other couples and best-friend duos. This month features Greg Barris and Roger Hailes.
“Tseng Kwong Chi: Performing for the Camera”; Grey Art Gallery/NYU, Greenwich Village, 11am. Free.
Tseng's photos of ’80s downtown nightlife, and his fish-out-of-water portraits of himself in a Mao suit posing against landmarks reemerge after 30 years of obscurity.
Deep Space; Cielo, Meatpacking District, 10pm. $20, with e-flyer free before 11pm or $12 after.
Dance-music deity François K's weekly Deep Space soiree focuses on dub in all its glorious, echo-drenched forms but extends its reach to all types of underground dance music.
Stargazing on the Highline; The High Line, Chelsea, 7:30pm. Free.
Use high-powered telescopes to see past the city's glow to the rest of the cosmos. No really, nature really is that fascinating.
Eat, Drink & Be Literary; BAMcafé, Fort Greene, 6:30pm. $60.
Dinner and a brilliant author, what more do you want? While you binge at the buffet, graphic novelist Chris Ware talks with The Paris Review editor Lorin Stein about his work.
Ari Hoenig; Smalls, West Village, 10:30pm. $20.
Along with his superb band, postbop daredevil Ari Hoenig turns small-group jazz into a thrilling high-wire act. Don't take the drummer's intermittent Monday night residency for granted.
John Mellencamp; Carnegie Hall, Midtown West, 8pm. $49.50–$129.50.
Expect that spirit of frankness to carry over into these gigs, which cover his classic hits as well as cuts from his new LP, Plain Spoken.
A Discussion with Renata Adler; BookCourt, Boerum Hill, 7pm. Free.
Don't miss a rare chance to see the illustrious novelist and journalist in person as she launches her much-anticipated new book of collected funch
Mark Morris Dance Group; BAM Howard Gilman Opera House, Fort Greene, 7:30pm. $25–$85
The master choreographer presents his company in two excellent programs that include Spring, Spring Spring, as well as two of his stellar dances set to music by Lou Harrison.
Literary Death Match; The Bell House, Gowanus, 8:15pm. $12, advance $8.
Four writers, two rounds, one winner. See when survives when Eliza Kennedy, Lane Moore, Kent Russel and Josh Gondelman battle, story against story.
ComedyJuice; Gotham Comedy Club, Chelsea, 9:30pm. $15 plus two-drink minimum.
This revered weekly show features lots of worthy local stand-ups and often one or two big names. Previous guests include Todd Barry and Jared Logan.
"Basquiat: The Unknown Notebooks"; Brooklyn Museum, Prospect Park, 11am. $16.
This show presents some 160 pages culled from the artist’s notebooks—sketches, the artist’s poetry and other writings—along with related paintings.
Yoga Journal Live!; Locations vary, 9am. Single class pass tba, All access pass $969.
Get Zen at this five-day yogacentric seminar featuring lectures, classes and a free market equipped with yoga apparel, jewelry and health food to help you move into the right mental space.
BritBits 8; Location TBA, 7:30pm, Free.
Theater company Mind the Gap brings you 16 short plays about the British for absolutely free as part of a series last presented in 2010. The catch? The new private venue (address disclosed upon reservation) seats just 30 people, so better request a spot on the website.
Gregory Charles: Vintage Live!; Le Qube, West Village, 8pm. $49–$69, VIP $149.
The prodigious Gregory Charles has made a big name for himself in his native Canada with his showmanship and unusually large repertoire (more than 14,000 songs, by his count), which lets him and his band build whole shows on the fly, out of requests from the audience.