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As famous for its 4am closing time as for its long lines, this downtown haunt has been an after-hours magnet for clubbers, clocked-out chefs and ne'er-do-wells since 1992. The restaurant's trappings—brick walls, globe lamps, slanted mirrors—reflect the bistro menu (hanger steak, escargot), but seafood is also a big focus: Look out for the raw-bar towers.