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The weirdest coupling since Tom Cruise and Cher, this Lower East Side den is one part Neapolitan trattoria and one part Asian cocktail bar. The bi-level space is a cross-cultural blend of Venetian plaster, chinoiserie accents and Buddha statues. In the 44-seat upstairs restaurant, decorated with tufted booths and marble tables, Naples native Pasquale Frola offers Southern Italian specialties (balsamic-drizzled crudi, tagliatelle with caramelized fennel), while pizzaiolo Michele Bisogno pulls novel pies (mushroom-and-mashed-potato, sausage-and-broccoli-rabe) from a wood-burning oven. Frola delves into heartier stock in the 16-seat private dining room, carving large-format feasts (deboned rib eye, whole-roasted duck) tableside. Down a flight of stairs, the cocktail bar—outfitted with chocolate wainscoting and a rosewood bar—offers smaller plates and Asian-inflected quaffs, with a nightly lineup of DJs behind the decks.