On the Evolutionary Function of Shame

D.A. Mindell's play juxtaposes Adam and Eve in the aftermath of their expulsion from Eden with the dilemma of a modern-day pregnant transgender man and his twin sister, a genetic scientist who has made an important discovery about gender dysphoria. Jess McLeod directs the world premiere for Second Stage, which has recently been cast out of its own little corner of heaven—midtown's Tony Kiser Theater—but has found shelter at the Signature Theatre complex.