Treat yourself to a room in the best luxury hotels in San Francisco

The Hotel Drisco is a sophisticated and welcoming boutique hotel situated in the posh Pacific Heights neighborhood with luxury amenities like nightly wine receptions and weekday chauffeur service. 

Time Out tip: The complimentary evening wine reception is not to be missed. There are local California wines, artisanal cheeses and charcuterie, fresh fruit and hot hors d’oeuvres, including delicious meatballs that could definitely spoil dinner.

Omni offers fine dining and award-winning service within walking distance from Union Square, a mecca of high-end shopping and art galleries. 

Time Out tip: The Omni has a fitness center, but guests can also request a Get Fit Kit, that includes a five-pound kettlebell, mini contour weights, a foam roller, push-up bars and a yoga mat.

The Michelin-starred restaurant is the biggest draw at this recently renovated luxury hotel in Union Square, just steps from some of the best shopping and eating in San Francisco.  

Time Out tip: The least expensive rooms at the hotel are very small. Those who can afford it should pay to upgrade.

This residence-style hotel is located in Ghirardelli Square, home to the famous chocolate company, several wine tasting rooms, a beer garden, tasty restaurants and boutique shops. 

Time Out tip: Since the room is so pricey, save money on dinner by dining at McCormick and Kuleto’s in Ghiradelli Square. The views are amazing and a cheeseburger and fries are just $5.50 during happy hour.

Magnificent views of the San Francisco Bay draw visitors to this chic boutique hotel on The Embarcadero with an aesthetic that is part mid-century modern, part urban cool.

Time Out tip: Hotel Vitale's complimentary rooftop yoga is the perfect way to prepare for a day of wandering the city (and eating a lot). 

Pretend you're San Francisco royalty (or an old timey railroad tycoon) at this elegant and sophisticated hotel in one of the city's most historic neighborhoods with gorgeous views of the bay. 

Time Out tip: Save money on cabs by using the complimentary weekday town car service.

Everything about this classy hotel screams San Francisco, from the Julia Morgan-designed building and gorgeous bay views to the state-of-the-art wellness spa and the iconic tiki bar in the basement. 

Time Out tip: Don’t miss dinner or drinks at the iconic Tonga Room & Hurricane Bar, a tiki bar with a floating band in a lagoon, surprise thunderstorms and mai tais served in fake coconuts.

The Ritz-Carlton is as luxurious as it gets. The landmark hotel, housed in a mansion atop Nob Hill, treats guests with butler service, a wine tasting lounge and complimentary car service. 

Time Out tip: A complimentary house car is available for trips within one mile of the hotel.

It's the world class spa that keeps visitors and locals coming back to this Nob Hill spot. The colorful Moroccan-themed rooms and stunning views of Grace Cathedral don't hurt either. 

Time Out tip: Street parking is possible and will save $59 a day.

For those who want to be in the thick of it, you can't do better than the Four Seasons, which offers endless amenities in a convenient location on the city's main thoroughfare, close to Union Square, SoMa and the Financial District. 

Time Out tip: The Den is a monthly cocktail series that pays homage to SF’s original speakeasies. Gain entrance by emailing theden@fourseasons.com to get the password.